Found 1561 of ic50 for VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 1
having polymerids = 690,50002109 and
complexids = 219,50000604
having polymerids = 690,50002109 and
complexids = 219,50000604
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Fuzhou University
Curated by ChEMBL
Fuzhou University
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of VEGFR1 (unknown origin)More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Fuzhou University
Curated by ChEMBL
Fuzhou University
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of VEGFR1 (unknown origin)More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Fuzhou University
Curated by ChEMBL
Fuzhou University
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of VEGFR1 (unknown origin)More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Fuzhou University
Curated by ChEMBL
Fuzhou University
Curated by ChEMBL
Affinity DataIC50: 0.210nMAssay Description:Inhibition of VEGFR1More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Fuzhou University
Curated by ChEMBL
Fuzhou University
Curated by ChEMBL
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Fuzhou University
Curated by ChEMBL
Fuzhou University
Curated by ChEMBL
Affinity DataIC50: 0.800nMAssay Description:Inhibition of VEGFR1More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Fuzhou University
Curated by ChEMBL
Fuzhou University
Curated by ChEMBL
Affinity DataIC50: >1nMAssay Description:Inhibition of VEGFR1 (unknown origin)More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Fuzhou University
Curated by ChEMBL
Fuzhou University
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant VEGFR-1 (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Fuzhou University
Curated by ChEMBL
Fuzhou University
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of human VEGFR1 in HUVEC cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Fuzhou University
Curated by ChEMBL
Fuzhou University
Curated by ChEMBL
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Fuzhou University
Curated by ChEMBL
Fuzhou University
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of N-terminal GST-tagged Flt1 using poly(Glu,Tyr) as substrate after 60 mins by alphascreen assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of VEGF-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Fuzhou University
Curated by ChEMBL
Fuzhou University
Curated by ChEMBL
Affinity DataIC50: 1.25nMpH: 7.1 T: 2°CAssay Description:To determine the activity of the various kinases, a homogenous time-resolved fluorescence (HTRF) in vitro kinase assay was used. (Mathis, G., HTRF(R)...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Fuzhou University
Curated by ChEMBL
Fuzhou University
Curated by ChEMBL
Affinity DataIC50: 1.45nMpH: 7.1 T: 2°CAssay Description:To determine the activity of the various kinases, a homogenous time-resolved fluorescence (HTRF) in vitro kinase assay was used. (Mathis, G., HTRF(R)...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Fuzhou University
Curated by ChEMBL
Fuzhou University
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Inhibition of VEGFR1 (unknown origin)More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.80nMAssay Description:Inhibition of VEGF-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Fuzhou University
Curated by ChEMBL
Fuzhou University
Curated by ChEMBL
Affinity DataIC50: 1.90nMpH: 7.1 T: 2°CAssay Description:To determine the activity of the various kinases, a homogenous time-resolved fluorescence (HTRF) in vitro kinase assay was used. (Mathis, G., HTRF(R)...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Fuzhou University
Curated by ChEMBL
Fuzhou University
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:The cytoplasmic domain of the human VEGF receptor (VEGFR-2) was expressed as a Histidine-tagged fusion protein following infection of insect cells us...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Fuzhou University
Curated by ChEMBL
Fuzhou University
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of VEGFR1 (unknown origin)More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Fuzhou University
Curated by ChEMBL
Fuzhou University
Curated by ChEMBL
Affinity DataIC50: 2nMpH: 7.2 T: 2°CAssay Description:Kinase assays were performed in 96 well microtiter plates that were coated overnight with 30.mu.g of poly-Glu-Tyr (4:1) in 10 mM Phosphate Buffered S...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Fuzhou University
Curated by ChEMBL
Fuzhou University
Curated by ChEMBL
Affinity DataIC50: 2nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Fuzhou University
Curated by ChEMBL
Fuzhou University
Curated by ChEMBL
Affinity DataIC50: <2nMpH: 7.4 T: 2°CAssay Description:An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Fuzhou University
Curated by ChEMBL
Fuzhou University
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of FLT1 by Hot Spot filtration binding assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Fuzhou University
Curated by ChEMBL
Fuzhou University
Curated by ChEMBL
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Fuzhou University
Curated by ChEMBL
Fuzhou University
Curated by ChEMBL
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Fuzhou University
Curated by ChEMBL
Fuzhou University
Curated by ChEMBL
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Fuzhou University
Curated by ChEMBL
Fuzhou University
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of VEGFR1 (unknown origin)More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Fuzhou University
Curated by ChEMBL
Fuzhou University
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against Vascular endothelial growth factor receptorMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibitory activity towards acetylcholine esterase (AChE)More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Fuzhou University
Curated by ChEMBL
Fuzhou University
Curated by ChEMBL
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Fuzhou University
Curated by ChEMBL
Fuzhou University
Curated by ChEMBL
Affinity DataIC50: 2.04nMpH: 7.1 T: 2°CAssay Description:To determine the activity of the various kinases, a homogenous time-resolved fluorescence (HTRF) in vitro kinase assay was used. (Mathis, G., HTRF(R)...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 2.10nMAssay Description:Inhibition of VEGF-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 2.10nMAssay Description:Inhibition of VEGF-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Fuzhou University
Curated by ChEMBL
Fuzhou University
Curated by ChEMBL
Affinity DataIC50: 2.10nMpH: 7.1 T: 2°CAssay Description:To determine the activity of the various kinases, a homogenous time-resolved fluorescence (HTRF) in vitro kinase assay was used. (Mathis, G., HTRF(R)...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Fuzhou University
Curated by ChEMBL
Fuzhou University
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:The cytoplasmic domain of the human VEGF receptor (VEGFR-2) was expressed as a Histidine-tagged fusion protein following infection of insect cells us...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Fuzhou University
Curated by ChEMBL
Fuzhou University
Curated by ChEMBL
Affinity DataIC50: 3nMpH: 7.2 T: 2°CAssay Description:Kinase assays were performed in 96 well microtiter plates that were coated overnight with 30 μg of poly-Glu-Tyr (4:1) in 10 mM Phosphate Buffered ...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Fuzhou University
Curated by ChEMBL
Fuzhou University
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of FLT1 (unknown origin)More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Fuzhou University
Curated by ChEMBL
Fuzhou University
Curated by ChEMBL
Affinity DataIC50: 3nMpH: 7.4 T: 2°CAssay Description:Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Fuzhou University
Curated by ChEMBL
Fuzhou University
Curated by ChEMBL
Affinity DataIC50: 3nMpH: 7.2 T: 2°CAssay Description:Kinase assays were performed in 96 well microtiter plates that were coated overnight with 30.mu.g of poly-Glu-Tyr (4:1) in 10 mM Phosphate Buffered S...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Fuzhou University
Curated by ChEMBL
Fuzhou University
Curated by ChEMBL
Affinity DataIC50: 3nMpH: 7.2 T: 2°CAssay Description:Kinase assays were performed in 96 well microtiter plates that were coated overnight with 30.mu.g of poly-Glu-Tyr (4:1) in 10 mM Phosphate Buffered S...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Fuzhou University
Curated by ChEMBL
Fuzhou University
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of human VEGFR1 using ATP as substrateMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Fuzhou University
Curated by ChEMBL
Fuzhou University
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:The cytoplasmic domain of the human VEGF receptor (VEGFR-2) was expressed as a Histidine-tagged fusion protein following infection of insect cells us...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Fuzhou University
Curated by ChEMBL
Fuzhou University
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of FLT1 by HTRF assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Fuzhou University
Curated by ChEMBL
Fuzhou University
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of Flt1 (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Fuzhou University
Curated by ChEMBL
Fuzhou University
Curated by ChEMBL
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Fuzhou University
Curated by ChEMBL
Fuzhou University
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of VEGFR-1 (unknown origin) by tumor cell growth inhibition assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Fuzhou University
Curated by ChEMBL
Fuzhou University
Curated by ChEMBL
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Fuzhou University
Curated by ChEMBL
Fuzhou University
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against Vascular endothelial growth factor receptorMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Fuzhou University
Curated by ChEMBL
Fuzhou University
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against Vascular endothelial growth factor receptorMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Fuzhou University
Curated by ChEMBL
Fuzhou University
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against VEGFR1More data for this Ligand-Target Pair